ACUTE PRE-B LYMPHOBLASTIC LEUKEMIA AND CONGENITAL ANOMALIES IN A CHILD WITH A DE NOVO 22Q11.1Q11.22 DUPLICATION

Acute pre-B lymphoblastic leukemia and congenital anomalies in a child with a de novo 22q11.1q11.22 duplication

Microdeletions and microduplications are recurrent in the q11.2 region of chromosome 22.The 22q11.2 duplication syndrome is an extremely variable disorder with a phenotype ranging from severe intellectual disability, facial dysmorphism, heart defects, and urogenital abnormalities to very mild symptoms.Both benign and malignant hematological entitie

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The developmental variations of the sagitta otolith in the young and mature male of a hermaphrodite polynemidae fish, Eleutheronema tetradactylum (Shaw, 1804)

Abstract The Eleutheronema tetradactylum is a protandrous, hermaphrodite, marine perciformes fish.The body length of this fish acts as an important diagnostic marker for male and female discrimination.The present study describes for the first time the ultrastructural characteristics on the medial surface of the sagitta otolith in different body siz

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